Professor Jeh-Jeng Wang


jjw      

Lab: Bioorganic Chemistry Laboratory (N842)

Tel: 886-7-3121101 ext. 2275

Fax: 886-7-3125339

E-mail: jjwang@kmu.edu.tw

 

Education and Experience:

  • B.S., Chemistry, National Chung-Hsing University, Taiwan (1975-1979)

  • Ph.D., Chemistry, The Ohio State Univ. USA (1983-1989)

  • Teaching Assistant, National Chung-Hsing University, Taiwan (1981-1983)

  • Postdoctoral fellow, College of Pharmacy, Univ. of Texas at Austin (1989-1991)

  • Associate Professor, Department of Medicinal and Applied Chemistry, Kaohsiung Medical University (1991-2001

  • Professor, Department of Medicinal and Applied Chemistry, Kaohsiung Medical University (2001-).

  • Director, Preparatory Office of Department of Biotechnology, Kaohsiung Medical University (2002-2003).

  • Chairman, Department of Biotechnology, Kaohsiung Medical University (2003-2004).

  • Dean, College of Life Sciences, Kaohsiung Medical University (2006 -2012).

Research Interests:

  • Design and synthesis of biological active compounds.

  • Organic reaction study.

  • Chemical biology.

 

研究成果目錄:()論文及著述

A. 期刊論文(近五年)

1.      C. Y. Chen, C. H. Yang, W. P. Hu, J. K. Vandavasi, M. I. Chung, and J. J. Wang*, “Synthesis of Fused Triazolo[4,5-d] Quinoline/ Chromene/ Thiochromene Derivates via Palladium Catalysis Mediated by Tetrabutylammonium Iodide”, RSC Advances, 2013, 3, 2710-2719.

2.      C. Y. Chen, Y. K. Chen, J. J. Wang, C. C. Hsu, F. Y. Tsai, P. J. Sung, H. C. Lin, L. S. Chang, W. P. Hu*,DC-81-enediyne induces apoptosis of human melanoma A375 cells: Involvement of the ROS, p38 MAPK, and AP-1 signaling pathways”, Cell Biology and Toxicology 2013, 29, 85-99.

3.      H. Y. Hsieh, W. C. Lee, G. C. Senadi, W. P. Hu*, J. J. Liang, T. R. Tsai, Y. W. Chou, K. K. Kou, C. Y. Chen, and J. J. Wang*, “Discovery, Synthetic Methodology and Biological Evaluation for Anti-Photoaging Activity of Bicyclic[1,2,3]Triazoles: In Vitro and in Vivo Studies”, J. Med. Chem. 2013, 56, 5422-5435.

4.      J. K. Vandavasi, K. K. Kuo, W. P. Hu, H. C. Shen, W. S. Lo, and J. J. Wang*,A Convenient Method to Construct (Z)-O xazines via 6-Exo-dig Iodocylization and Synthesis of Indolin-3-one” Org. & Biomol. Chem. 2013, 11, 6520-6525.

5.      C. Y. Chen, W. P. Hu, M. C. Liu, P. C. Yan, and J. J. Wang*, M. I. Chung, “Efficient Synthesis of Quinazolines with Hypervalent Iodine as a Catalyst”, Tetrahedron 2013, 69, 9735-9741.

6.      C. Y. Chen, P. H. Lee, Y. Y. Lin, W. T. Yu, W. P. Hu,* Chia-Chen Hsu, Y. T. Lin, L. S. Chang, C. T. Hsiao, J. J. Wang*, Mei-Ing Chung, “Synthesis, DNA-binding Abilities and Anticancer Activities of Triazole-Pyrrolo[2,1-c][1,4] benzodiazepines Hybrid Scaffolds”, Bioorg. Med. Chem. Lett. 2013, 23, 6854-6859.

7.      S. S. K. Boominathan, W. P. Hu, G. C. Senadi, and J. J. Wang*, “Silver(I)-Catalyzed Conia-Ene Reaction: Synthesis of 3-Pyrrolines via 5-Endo-Dig Cyclization, Adv. Syn. & Cat. 2013, 355, 3570-3574.

8.      G. C. Senadi, W. P. Hu, S. S. K. Boominathan, and J. J. Wang*, “Nickel or Palladium Catalyzed Stereoselective Synthesis of Tetrasubstituted Olefinic Indoline Fused Triazoles: Extension to Spiroindoline Core”, Adv. Syn. & Cat. 2013, 355, 3679-3693.

9.      C. Y. Chen, W. P. Hu, P. C. Yan, G. C. Senadi,  and J. J. Wang*, “Metal Free, Acid-Promoted Synthesis of Imidazole Derivatives via Multi-Component Reaction , Org. Lett. 2013, 15, 6116-6119.

10.  B. D. Barve, Y. C. Wu, M. El-Shazly, D. W. Chuang, Y. B. Cheng, J. J. Wang*, and F. R. Chang*, “Copper-Catalyzed Oxidative Coupling of Formamides with Salicylaldehydes: Synthesis of Carbamates in the Presence of a Sensitive Aldehyde Group”, J. Org. Chem. 2014, 15, 3206-3214.

11.  B. D. Barve, Y. C. Wu, M. El-Shazly, M. Korinek, Y. B. Cheng, J. J. Wang*, and F. R. Chang*, “Iron-Catalyzed Oxidative Direct α-C−H Bond Functionalization of Cyclic Ethers: Selective C−O Bond Formation in the Presence of a Labile Aldehyde Group”, Org. Lett. 2014, 16, 1912-1915.

12.  M. El-Shazly, B. D. Barve, M. Korinek, J.R. Liou, D. W. Chuang, Y. B. Cheng, M. F. Hou, J. J. Wang, Y. C. Wu*, and F. R. Chang*,, Insights on the Isolation, Biological Activity and Synthetic Protocols of Enyne Derivatives”, Current Topics in Medicinal Chemistry, 2014, 14, 1076-1093.

13.  S. S. K. Boominathan, W. P. Hu, G. C. Senadi, J. K. Vandavasi, and J. J. Wang*,A one-pot hypoiodite catalysed oxidative cycloetherification approach to benzoxazoles”, ChemComm., 2014,50, 6726-6728.

14.  Yin-Kai Chen, Gopal Chandru Senadi, Chih-Hung Lee, Yi-Min Tsai, Yan-Ren Chen, Wan-ping    Hu,* Yu-Wei Chou, Kung-Kai Kuo, and Jeh-Jeng Wang*, “Apoptosis Induced by 2 Aryl Benzothiazoles-Mediated Photodynamic Therapy in Melanomas via Mitochondrial Dysfunction”, Chem. Res. Toxico. 2014, 27, 1187-1198.

15.  J. K. Vandavasi, W. P. Hu, G. C. Senadi, S. S. K. Boominathan, H. Y. Chen,* and J. J. Wang*, “A K2CO3 mediated regioselective synthesis of indole/pyrrole-fused 1,4-oxazines: An unexpected indole-fused azlactone synthesis”, Euro. J. Org. Chem. 2014, 6219-622.

16.  Jaya Kishore Vandavasi, Wan-Ping Hu, Cheng-Tien Hsiao, Gopal Chandru Senadi, Jeh-Jeng Wang*, “A New Approach for Fused Isoindolines via hexadehydro-Diels-Alder Reaction (HDDA) by Fe (0) Catalysis ”, RSC Advances 2014, 57547-57552.

17.  C.-S. Wu*, H.-Y. Kuo, W.-P. Hu, J.-J. Wang, A.-H. Fang and L.-Y. Tien, “The ultraviolet A-activated photosensitizer 2-(4-aminophenyl)-7-methoxybenzothiazole suppresses proliferation and induces apoptosis of keloid fibroblasts: a potential adjunctive therapy for keloids”, Clinical and Experimental Dermatology 2015, 40, 63–70.

18.  Gopal Chandru Senadi, Wan-Ping Hu, Siva Senthil Kumar Boominathan, and Jeh-Jeng Wang*, “Palladium(0)-Catalyzed Single and Double Isonitrile Insertion: AFacile Synthesis of Benzofurans, Indoles, and Isatins”, Chem. Euro. J. 2015, 21, 998-1003.

19.  Siva Senthil Kumar Boominathan, Gopal Chandru Senadi, Jaya Kishore Vandavasi, Jeff Yi-Fu Chen, and Jeh-Jeng Wang*, An Iron Catalyzed Cascade Approach to Benzo[b]carbazoles Synthesis followed by 1,4-Sulfonyl migration”, Chem. Euro. J. 2015, 21, 3193-3197.

20.  Gopal Chandru Senadi, Wan-Ping Hu, Ting-Yi Lu, Amol Garkhedkar, Jaya Kishore Vandavasi, and Jeh-Jeng Wang*, “I2-TBHP-Catalyzed Oxidative Cross-coupling of N-sulfonyl hydrazones and Isocyanides to5-aminopyrazoles”, Org. Lett. 2015, 17, 1521-1524.

21.  Balaji D. Barve, Yang-Chang Wu, Mohamed El-Shazly, Michal Korinek, Yuan-Bin Cheng, Jeh-Jeng Wang*, Fang-Rong Chang*,Copper-catalyzed selective C-O bond formation by oxidative a-C(sp3)-H/O-H coupling between ethers and salicylaldehydes”, Tetrahedron 2015, 71, 2290-2297.

22.  Jaya Kishore Vandavasi, Cheng-Tien Hsiao, Wan-Ping Hu, Siva Senthil Kumar Boominathan, and Jeh-Jeng Wang*, “Silver (I)-Catalyzed Tandem Approach to b-Ketoamides”, Euro. J. Org. Chem. 2015, 3171-3177.

23.  Jaya Kishore Vandavasi, Wan-Ping Hu, Siva Senthil Kumar Boominathan, Bing-Chun Guo, Cheng-Tien Hsiao and Jeh-Jeng Wang*, “Au (I)-Catalyzed Synthesis of 8-Oxabicyclo[3.2.1]oct-2-enes and 9-Oxabicyclo[3.3.1]nona-2,6-dienes from Enynol via Oxonium/Prins-type Cyclization”, ChemComm., 2015, 51, 12435-12438.

24.  Siva Senthil Kumar Boominathan, Chung-Yu Chen, Po-Jui Huang, Ruei-Jhih Hou, Jeh-Jeng Wang*, “A Sequential One-pot Approach to 1,2,4,5-Tetrasubstituted-2H-imidazole Synthesis from Disubstituted Alkynes”, New J. Chem. 2015, 39, 6914-6918.

25.  Ping-Fan Chen, Kung-Kai Kuo, Jaya Kishore Vandavasi, Siva Senthil Kumar Boominathan, Chung-Yu Chen and Jeh-Jeng Wang*, “Metal-free cycloaddition to synthesize naphtho[2,3-d][1,2,3]triazole-4,9-diones”, Org. & Biomol. Chem. 2015, 13, 9261-9266.

26.  Gopal Chandru Senadi, Wan-Ping Hu, Amol Milind Garkhedkar, Siva Senthil Kumar Boominathan and Jeh-Jeng Wang*, “Palladium(II)-catalysed regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstitutedpyrroles from alkenes via anti-Markovnikovselectivity”, ChemComm., 2015, 51, 13795-13798.

27.  Jaya Kishore Vandavasi, Wan-Ping Hu, Gopal Chandru Senadi, Hui-Ting Chen, Hsing-Yin Chen, Kuang-Chan Hsieh, and Jeh-Jeng Wang*, “Aryl l3-iodane-mediated 6-exo-trig cyclization for synthesizing highly substituted chiral morpholines”,  Adv. Syn. & Cat. 2015, 357, 3570-3574.

28.  W-Ping Hu, Chia-Chen Hsu, Ya-Ching Wang, Gopal Chandru Sendai, Kung-Kai Kuo, Jen-Fon Jen and Jeh-Jeng Wang*, “Bis(phenylidenebenzeneamine)-1-disulfide Derivatives Induce Autophagy in Melanoma cells Through a Mitochondria-mediated Pathway”, Anticancer Research 2015, 35, 6075-6080.

29.  Siva Senthil Kumar Boominathan, and Jeh-Jeng Wang*, “A Palladium and Copper Catalyzed Synthesis of Dihydro[1,2-b]indenoindole-9-ol and Benzofuro[3,2-b]indolines: Metal Controlled Intramolecular C-C and C-O Bond Forming Reactions”, Chem. Euro. J. (Hot Paper). 2015, 21, 17044-17050.

30.  Yu-Wei Chou, Gopal Chandru Senadi, Chung-Yu Chen, Kung-Kai Kuo, Ying-Ting Lin, Jeh-Jeng Wang, Jia-Hau Lee, Ya-Ching Wang, Wan-Ping Hu,* “Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as

p53-dependent and -independent apoptogenic signaling in melanoma cells”, Euro. J. Med. Chem. 2016, 109, 59-74.

31.  Jia-Heng Jiang, Siva Senthil Kumar Boominathan, Wan-Ping Hu, Chung-Yu Chen, Jaya Kishore Vandavasi, Ying-Ting Lin, and Jeh-Jeng Wang*, “Sequential, One-Pot Access to Arylated Benzoquinones/Naphthoquinones from Phenols/Naphthols”, Euro. J. Org. Chem. 2016, (13), 2284-2289.

32.  Gopal Chandru Senadi, Jie-Ming Liao, Kung-Kai Kuo, Jian-Cheng Lin, Long-Sen Chang, Jeh Jeng Wang, Wan-Ping Hu,* “Design, Synthesis and Antimetastatic Evaluation of 1-benzothiazolylphenylbenzotriazoles for Photodynamic Therapy in Oral Cancer Cells”, MedChemComm 2016, 7, 1151-1158.

33.  Gopal Chandru Senadi, Babasaheb Sopan Gore, Wan-Ping Hu, and Jeh-Jeng Wang*, “BF3-Etherate-Promoted Cascade Reaction of 2-Alkynylanilines with Nitriles: One-Pot Assembly of 4-Amido-Cinnolines”, Org. Lett. 2016, 18, 2890-2893.

34.  Chung-Yu Chen, Gopal Chandru Senadi, Mei-Chun Liu, and Jeh-Jeng Wang*, “Halogenation of Arenes via an In situ Generated Hypohalous Acid from m-CPBA and HX: Mechanistic Insights from Cyclic Voltammetry”, Chemistryselect 2016, 1, 2207-2211.

35.  Siva Senthil Kumar Boominathan, Ruei-Jhih Hou, Wan-Ping Hu, Po-Jui Huang, and Jeh-Jeng Wang*, “A palladium catalyzed domino approach to 2,3-disubstituted benzofurans via intermolecular carbopalladation/C(sp3)-H functionalization/isomerization sequence”, Adv. Syn. & Cat. 2016, 358, 2984-2989.

36.  Gopal Chandru Senadi, Bing-Chun Guo, Wan-Ping Hu, and Jeh-Jeng Wang*, “Iodine-promoted cyclization of N-propynyl amides and N-allyl amides via sulfonylation and sulfenylation”, ChemComm. 2016, 52, 11410-11413.

37.  Kung-Kai Kuo, Siva Senthil Kumar Boominathan, Jaya Kishore Vandavasi, Jia-Shing Hsiao, Jeh-Jeng Wang, and Wan-Ping Hu*, “Copper-Catalyzed One-pot Process to Construct Triazole-Linked Urea Derivatives”, Synthetic Comm. 2016, 46, 1612-1618.

38.  Gopal Chandru Senadi, Ganesh Kumar Dhandabani, Wan-Ping Hu and Jeh-Jeng Wang*, “Metal-free annulation/aerobic oxidative dehydrogenation of cyclohexanones with o-acylanilines: efficient syntheses of acridines”, Green Chem. 2016, 18, 6241-6245.

39.  Siva K. Reddy Kotla, Jaya Kishore Vandavasi, Jeh-Jeng Wang, Keykavous Parang, and Rakesh K. Tiwari*, “Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2 a]pyrimidines and Pyrazolo[1,5a]pyrimidines”, ACS Omega. 2017, 2, 11-19.

40.  Amol Milind Garkhedkar, Gopal Chandru Senadi, and Jeh-Jeng Wang*, “ZnBr2Mediated Cascade Reaction of o-Alkoxy Alkynols: Synthesis of Indeno[1,2-c]chromenes”, Org. Lett. 2017, 19, 488-491.

41.  Siva Senthil Kumar Boominathan, Mutra Mohana Reddy, Ruei-Jhih Hou, Hui-Fen Chena and Jeh-Jeng Wang*, “A simple and efficient method for constructing azepino[4,5-b]indole derivatives via acid catalysis”, Org. & Biomol. Chem. 2017, 15, 1872-1875.

42.  Gopal Chandru Senadi, Ting-Yi Lu, Ganesh Kumar Dhandabani, and Jeh-Jeng Wang*, “Palladium-Catalyzed Double-Isocyanide Insertion via Oxidative N-O Cleavage of Acetyl Oximes: Syntheses of 2H-Pyrrol-2-imines”, Org. Lett. 2017, 19, 1172-1175.

43.  Siva Senthil Kumar Boominathan, and Jeh-Jeng Wang*,Rapid access to indeno[1,2-c]quinolines via Brønsted-Acid Catalyzed Cascade Reaction”, Adv. Syn. & Cat. 2017, 359, 1844-1848.

44.  Gopal Chandru Senadi, Ji-Qi Wang, Babasaheb Sopan Gore, and Jeh-Jeng Wang *, “Pd(dba)2/tBuONO-Catalyzed Cyclization of o-Alkynylanilines with tBuONO: Synthesis and Applications of Indazole 2-oxides”, Adv. Syn. & Cat. 2017, 359, 2747-2753.

45.  Babasaheb Sopan Gore, Gopal Chandru Senadi, Amol Milind Garkhedkar and Jeh-Jeng Wang*, “Efficient Approach to Amide Bond Formation with Nitriles and Peroxides: One-pot Access to Boronated β-Ketoamides”, Adv. Syn. & Cat. 2017, 359, 3014-3021.

46.  Gopal Chandru Senadi, Mutra Mohana Reddy, Ting-Yi Lu and Jeh -Jeng Wang*, “Oximes as a Recyclable Template for the Synthesis of Ureas and Carbamates by an In Situ Generation of Carbamoyl Oximes”, Green Chem. 2017, 19, 4272-4277.

47.  Wan-Ping Hu, Kung-Kai Kuo, Gopal Chandru Senadi, Long-Sen Chang and Jeh-Jeng Wang, Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells” Anticancer Research, 2017, 37, 10, 5499-5055.

48.  Gopal Chandru Senadi, Bing-Chun Guo, Yu-Ching Chang, Wan-Ping Hu and Jeh-Jeng Wang*, “Synthesis of Fused-Pyrazines via Palladium-Catalyzed Double Benzyl Isocyanide Insertion and Cross-Dehydrogenative Coupling” Adv. Syn. & Cat. 2018, 360, 491-501.

49.   Gopal Chandru Senadi and  Jeh-Jeng Wang*, “p-TsOH Promoted Synthesis of Benzo-Fused O-Heterocycles from Alkynols via Ring Contraction and C-O Scission Strategy” Green Chem., 2018, Accepted manuscript.

B.  研討會論文

1.          Da-Wei Chuang; Mohamed El-Shazly, Balaji D. Barve, Jeh-Jeng Wang, Fang-Rong Chang, Yang-Chang Wu (Apr. 2013). “Efficient approach for the synthesis of γ-benzopyranones as natural product intermediates utilizing Sonogashira coupling and 18-crown-6 ether mediated cyclization” 245th American Chemical Society National Meeting, New Orleans, U. S. A.

2.          Jaya Kishore Vandavasi and Jeh-Jeng Wang (Nov. 2013) “Stereo, regio and chemoselective reactions to synthesize 1,3-oxazines with iodine as a dual role”, The 11th International Symposium on Organic Reactions (ISOR-2013), Taipei, Taiwan.

3.          Gopal Chandru Senadi (Poster Award), Wan-Ping Hu, Jeh Jeng Wang (Nov. 2013) “Facile selective and regiocontrolled synthesis of oxazolines and oxazoles mediated by ZnI2 and FeCl3”, The 11th International Symposium on Organic Reactions (ISOR-2013), Taipei, Taiwan.

4.          Balaji D. Barve, Da-Wei Chuang, Mohamed El-Shazly, Chin-Chau Chen, Yu-Ming Chung, Ming-Jung Wu, Fang-Rong Chang, Jeh-Jeng Wang ,Yang-Chang Wu (Nov. 2013) “An aqueous B-alkyl Suzuki cross coupling reaction for the synthesis novel 1,5-diphenylpent-3-en-1-yne derivatives”, The Chinese Chemical Society Annual Meeting,Nantou, Taiwan.

5.          Beb-Fun Chen, Jeh-Jeng Wang (Nov. 2013), “Efficient Synthesis of Quinoxalines with Hypervalent Iodine as a Catalyst” The Chinese Chemical Society Annual Meeting,Nantou, Taiwan.

6.          Siva Senthil Kumar, Jaya Kishore Vandavasi, Wan-Ping Hu and Jeh-Jeng Wang (Jul. 2014), “SILVER CATALYZED CONIA-ENE REACTION FOR 3-PYRROLINES SYNTHESIS VIA 5-ENDO DIG CYCLIZATION”, 14th Belgian Organic Synthesis Symposium (BOSS XIV).

7.          Balaji D. Barve, Yang-Chang Wu, Mohamed El-Shazly, Da-Wei Chuang, Yuan-Bin Cheng,Jeh-Jeng Wang, Fang-Rong Chang (Mar. 2015), “Selective carbamates synthesis by copper catalyzed oxidative coupling of formamides with salicylaldehydes”, 249th American Chemical Society National Meeting, Denver, CO, U. S. A.

8.          Jaya Kishore Vandavasi, Wan-Ping Hu,Jeh-Jeng Wang (Mar. 2015), “ A K2CO3 mediated regioselective synthesis of indole​/pyrrole-​fused 1, 4-​oxazines: An unexpected indole-​fused azlactone synthesis”, 249th American Chemical Society National Meeting, Denver, CO, U. S. A.

9.          王志鉦, 東海大學化學系邀請演講演 (May 2015), “New Synthetic Methodologies for Development of Heterocyclic Bioactive Molecules”, Taichung, Taiwan.

10.      Siva Senthil Kumar Boominathan, Jeh-Jeng Wang (Nov. 2015), “Divergent Synthesis of 3-pyrrolines/benzo[b]carbazoles/ α-keto benzoxazoles form ß-ketosulfonamides”, ICCEOCA-10, Kaohsiung, Taiwan.

11.      Gopal Chandru Senadi and Jeh-Jeng Wang (invited poster) (Dec. 2015), “Isocyanides as a Building Block for the Efficient Construction of Oxygen and Nitrogen Heterocycles”, The Chinese Chemical Society Annual Meeting, Hualien, Taiwan.

12.      Ting Yi Lu, Gopal Chandru Senadi and Jeh Jeng Wang (Dec. 2015), “I2−TBHP-Catalyzed Oxidative Cross-Coupling of N‑Sulfonyl Hydrazones and Isocyanides to 5‑Aminopyrazoles”, The Chinese Chemical Society Annual Meeting, Hualien, Taiwan.

13.      Ruei-Jhih Hou, Siva Senthil Kumar Boominathan, Jeh-Jeng Wang (Dec. 2015), “Sequential One-pot Approach to 1,2,4,5-Tetrasubstituted-2H-imidazole Synthesis from Disubstituted Alkynes”, The Chinese Chemical Society Annual Meeting, Hualien, Taiwan.

14.      Bing-Chun Guo, Jaya Kishore Vandavasi and Jeh Jeng Wang (Dec. 2015), “Au(I)-catalyzed synthesis of 8-oxabicyclo[3.2.1]oct-2-enes and 9-oxabicyclo[3.3.1]nona-2,6-dienes from enynol via oxonium/Prins-type cyclization”, The Chinese Chemical Society Annual Meeting, Hualien, Taiwan.

15.      Siva Senthil Kumar Boominathan, Jeh-Jeng Wang (Mar. 2016), “A Palladium and Copper Catalyzed Synthesis of Dihydro[1,2-b]indenoindole-9-ol and Benzofuro[3,2-b]indolines: Metal Controlled Intramolecular C-C and C-O Bond Forming Reactions”, Chemistry Conference for Young Scientists – 2016, Blackenberge, Belgium.

16.      Siva Senthil Kumar Boominathan, Gopal Chandru Senadi and Jeh-Jeng Wang (Apr. 2016), “O-acyl anilines and enaminocarbonyls as a building block for the synthesis of oxygen and nitrogen heterocycles via transition metal catalysis”, The 12th International Symposium on Organic Reactions (ISOR-12), Kyoto, Japan.

17.      Gopal Chandru Senadi and Jeh-Jeng Wang (Aug. 2016), “I2-TBHP-Catalyzed Oxidative Cross-Coupling of N-Sulfonyl Hydrazones and Isocyanides to 5-Aminopyrazoles”, Kuching, Sarawak, Malysia.

18.      Gopal Chandru Senadi, and Jeh-Jeng Wang (Oct. 2016), “O-substituted anilines as a building block for the synthesis of oxygen and nitrogen heterocycles”, 11th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-11), Daejeon, Korea

19.      Babasaheb Sopan Gore, Ganesh Kumar Dhandabani, and Jeh-Jeng Wang (Dec. 2016), “BF3-Etherate-Promoted Cascade Reaction of 2-Alkynylanilines with Nitriles: One-Pot Assembly of 4-Amido-Cinnolines” The Chinese Chemical Society Annual Meeting, Taichung, Taiwan.

20.      Ganesh Kumar Dhandabani, Amol-Milind Garkhedkar and Jeh-Jeng Wang (Dec. 2016), “Metal-Free Annulation/Aerobic Oxidative Dehydrogenation of Cyclohexanones with o-Acylanilines: Efficient Syntheses of Acridines” The Chinese Chemical Society Annual Meeting, Taichung, Taiwan.

21.      Amol Milind Garkhedkar, Babasaheb Sopan Gore and Jeh-Jeng Wang (Dec. 2016), “Palladium(II)-catalysed regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstituted pyrroles from alkenes via anti-Markovnikov selectivityThe Chinese Chemical Society Annual Meeting, Taichung, Taiwan.

22.      Mutra Mohana Reddy, Gopal Chandru Senadi, and Jeh-JengWang (Dec. 2016), “Iodine-promoted cyclization of N-propynyl amides and N-allyl amides via sulfonylation and sulfenylation” The Chinese Chemical Society Annual Meeting, Taichung, Taiwan.

23.      Senadi, Gopal Chandru;Wang, Jeh-Jeng (Apr. 2017), “o--Substituted anilines as a building block for the synthesis of aza heterocycles under transition-metal-free conditions”, 253rd American Chemical Society National Meeting, San Francisco, CA, U. S. A.

24.      Mutra, Mohana Reddy; Wang, Jeh-Jeng (Dec. 2017), “Oximes as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes”, Chinese Chemical Society Annual Meeting, National Chiayi University, Chiayi city, Taiwan.

25.      Kudale Vishal; Wang, Jeh-Jeng (Dec. 2017), “Bis(dibenzylideneacetone) palladium(0)/tert- Butyl Nitrite- catalyzed Cyclization of o-Alkynylanilines with tert-Butyl Nitrite: Synthesis and Application of Indazole 2-Oxides”, Chinese Chemical Society Annual Meeting, National Chiayi University, Chiayi city, Taiwan.

26.      Dhandabani, Ganesh Kumar; Mutra, Mohana Reddy; Senadi, Gopal Chandru; Wang, Jeh-Jeng (Dec. 2017), “Effective synthetic method of 2HPyrrol-2-imines by Palladium Catalyzed Oxidative N−O Cleavage of Acetyl Oximes”, Chinese Chemical Society Annual Meeting, National Chiayi University, Chiayi city, Taiwan.

C. Patent

1.          王志鉦, 胡婉萍, 李文俊, 謝欣祐3-PED4HPT衍生物之合成與抗光老化活性之評估 TW 101125690, 2012-07-17, 中華民國專利2012, 101125690.

2.          王志鉦, 廖昭程,胡婉萍,沈鶴全”2-(4-胺苯)苯幷噻唑衍生物的合成與用途/ Synthesis of 2-(4-Aminophenyl)benzothiazole derivatives and use thereof” 2014--2030,中華民國專利第I444371.

3.          J. J. Wang, C. C. Liao, W. P. Hu, H. C. Shen, “Synthesis 2-(4-Aminophenyl)benzothiazole derivatives and use thereofU.S. Patent. 8592603 B2(2013-11-26).  

4.          王志鉦, 胡婉萍, 駱威勝 “雙(苯亞甲基-苯胺)二硫化合物之合成與抗癌活性之評估, 2013-2031, 中華民國專利第I398246.

5.          J. J. Wang, W. P. Hu, W. S. Lo “Synthesis and antitumor activity of novel bis(benzylidene-benzenamine)- disulfides” U. S. A. patent. 8680155B2 (2014).

6.          J. J. Wang, C. C. Liao, W. P. Hu, H. C. Shen, “Synthesis of 2 -(4-Aminophenyl)benzothiazole derivatives and use thereofU.S. Patent. 8927584 B2 (2015-1-6).

7.          王志鉦,強竹,王顗淇, ”Pd(dba)2/tBuONO催化與tBuONO環化o-Alkynylanilines:吲唑氧化胺的合成與應用中華民國專利2017, 申請中.

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