Professor Li-Fang Wang
Lab: N832, First Teaching Building
TEL: +886-7-3121101 ext. 2217
Fax: +886-7-3125339
E-mail:lfwang@kmu.edu.tw
Education
1979-1983 | B.S. in Chemistry (National Tsing Hua University, Hsinchu, Taiwan) |
1983-1985 | M.S. in Chem. Eng. (National Tsing Hua University, Hsinchu, Taiwan) |
1986-1990 | Ph.D. in Polymer Chem. (Polytechnic University, New York, USA) |
1990-1991 | Postdoc. in Biomed. Eng. (The Johns Hopkins Univ., Baltimore, USA) |
Professional Carrier
1991-2000 | Associate Professor, Dept. of Medicinal & Applied Chem, KMU, Taiwan |
2000-present | Professor, Dept. of Medicinal & Applied Chem., KMU, Taiwan. |
2003-2004 | Director, Research & Development Office, KMU, Taiwan |
2004-2005 | Visiting Professor, Biomed. Eng, The Johns Hopkins Univ., Baltimore, USA |
2006-2009 | Chairman, Dept. of Biotechnology, KMU, Taiwan |
2012- present | Dean, College of Life Science, KMU, Taiwan |
Scientific Activities and Honors
1991- | Committee Board for Chinese Biomaterials and Drug Delivery Society |
1991- | Grant Review Board for Ministry of Science and Technology of Taiwan |
2006-2009 | Panel Review Board for Taiwan National Science Council |
2011- | Executive committee for Chinese Chemical Society of Taipei, Kaohsiung Local Chapter |
2014- | Vice president of Controlled Release Society Taiwan Local Chapter |
2014- | Panel Review Board for SBIR projects of Taiwan |
Awards
1997 | Best Teaching Award from KaohsiungMedicalUniversity |
2012, 2013, 2014 | Excellence in Research Award from Kaohsiung Medical University |
2012, 2013, 2014 | Outstanding Research Award from the KMU Alumni Association |
2014 | Excellence in Research Award from Li Chio Zen (李昭仁) Biomaterial Research Foundation |
2009-2014 | Outstanding Paper Research Award from Kaohsiung Medical University |
2014 | Outstanding Patent Application Award from Kaohsiung Medical University |
Research Interests
1. Development of polymeric nanoparticles based on natural polysaccharides for anticancer drug and/or nucleic acid drug delivery
2. Construction of magnetic iron oxides for theranostic applications
3. Synthesis of amphiphilic block copolymers containing disulfides via ROP and ATRP for multifunctional biomedical applications
Membership
- American Chemical Society
- Controlled Release Society
- Controlled Release Society Taiwan Local Chapter
- Chinese Chemical Society of Taipei
- Chinese Polymer Society of Taipei
Publication lists
2021
1. ivasoorian Siva Sankari, Hans-Uwe Dahms, Ming-Fong Tsai, Yu-Lun Lo, Li-Fang Wang*, “Comparative study of an antimicrobial peptide and a neuropeptide conjugated with gold nanorods for the targeted photothermal killing of bacteria” Colloids and Surfaces B: Biointerfaces, 2021, 208: 112117 (https://doi.org/10.1016/j.colsurfb.2021.112117, IF=5.268, 11/71, Biophysics)
2. Venkatesh Ravula, Yu-Lun Lo, Li-Fang Wang*, and Srilakshmi V. Patri*, “Gemini lipopeptide bearing an ultrashort peptide for enhanced transfection efficiency and cancer-cell-specific cytotoxicity” ACS Omega, 2021, 6(35), 22955-22968.
3. Yu-Lun Lo, Xiao-Shan Huang, Hsuan-Ying Chen, Yuan-Chun Huang, Zi-Xian Liao, and Li-Fang Wang*, “ROP and ATRP fabricated redox sensitive micelles based on PCL-SS-PMAA diblock copolymers to co-deliver PTX and CDDP for lung cancer therapy"Colloids and Surfaces B: Biointerfaces, 2021, 198, 111443 (IF=5.268, 11/71, Biophysics)
4. Suman Chirra, Li-Fang Wang, Himanshu Aggarwal, Ming-Fong Tsai, Siva Sankari Soorian, Suresh Siliveri, Srinath Goskula, Sripal Reddy Gujjula, Venkatathri Narayanan*, "Rapid synthesis of a novel nano-crystalline mesoporous faujasite type metal-organic framework, ZIF-8 catalyst, its detailed characterization, and NaBH4 assisted, enhanced catalytic Rhodamine B degradation" Materials Today Communications 2021, 26: 101993 (IF=2.678, 151/314, MATERIALS SCIENCE, MULTIDISCIPLINARY - SCIE)
5. Venkatesh Ravula, Yu-Lun Lo, Yi-Ting Wu, Chien-Wen Chang, Srilakshmi V. Patri,* Li-Fang Wang*, “Arginine-tocopherol bioconjugated lipid vesicles for selective pTRAIL delivery and subsequent apoptosis induction in glioblastoma cells” Materials Science & Engineering C, 2021, 126(5), 112189, https://doi.org/10.1016/j.msec.2021.112189 (IF=7.328, 7/40, Materials Science: Biomaterials)
6. Mahendra Jadhao, Eing-Mei Tsai, Ho-Chun Yang, Yih-Fung Chen, Shih-Shin Liang, Tsu-Nai Wang, Yen-Ni Teng, Hurng-Wern Huang, Li-Fang Wang,* and Chien-Chih Chiu*, “The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS” Antioxidants, 2021, 10, 949 (IF=5.95 ).
7. Ming-Fong Tsai, Yu-Lun Lo, Yugendhar Soorni, Chia-Hao Su, Siva Sankari Sivasoorian, Jung-Yen Yang, and Li-Fang Wang,* “Near-Infrared Light-Triggered Drug Release from Ultraviolet- and Redox-Responsive Polymersome Encapsulated with Core−Shell Upconversion Nanoparticles for Cancer Therapy” ACS Appl. Bio Mater. 2021, 4, 3264−3275
2020
1. Yu-Lun Lo, Ming-Fong Tsai, Yugendhar Soorni, Chin Hsu, Zi-Xian Liao, and Li-Fang Wang*, “Dual Stimuli-Responsive Block Copolymers with Adjacent Redox-and Photo-Cleavable Linkages for Smart Drug Delivery” 2020, Biomacromolecules, 21 (8), 3342-3352. (IF:6.988, 5/88, Chemistry, Organic)
2. Ming-Fong Tsai, Yu-Lun Lo, Yuan-Chun Huang, Chun-Chieh Yu, Yi-Ting Wu, Chia-Hao Su*, and Li-Fang Wang*. "Multi-Stimuli-Responsive DOX Released from Magnetosome for Tumor Synergistic Theranostics." International Journal of Nanomedicine 2020, 15, 8623-8639. (IF:6.4, 28/275, Pharmacology & Pharmacy)
3. Sanford P.C. Hsu, Udesh Dhawan, Yuan-Yun Tseng, Ching-Po Lin, Ching-Yu Kuo, Li-Fang Wang, Ren-Jei Chung, “Glioma-sensitive delivery of Angiopep-2 conjugated iron gold alloy nanoparticles ensuring simultaneous tumor imaging and hyperthermia mediated cancer theranostics”. Appl. Mater. Today, 2020, 18, 100510. (IF:10.041, 39/335, Materials Science, Multidisciplinary)
4. Nisar, S.; Pandit, A. H.; Wang, L.-F*.; Rattan, S.*, Strategy to design a smart photocleavable and pH sensitive chitosan-based hydrogel through a novel crosslinker: a potential vehicle for controlled drug delivery. RSC Advances 2020, 10 (25), 14694-14704 (IF=3.361, 81/179, Chemistry, Multidisciplinary).
2019
1. Wangta Liu,# Yu-Lun Lo,# Chin Hsu, Yi-Ting Wu, Zi-Xian Liao, Wen-Jeng Wu, Yi-Jou Chen, Chieh Kao, Chien-Chih Chiu,* and Li-Fang Wang*, 2019, “CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC” Molecular Therapy- Nucleic Acids, 17(9), 477-490 (IF: 8.886, 15/136, MEDICINE, RESEARCH & EXPERIMENTAL-SCIE)
2. Tzu-Yun Chen, Chih-Lung Lin, Li-Fang Wang, Ke-Li Tsai, Jun-Yu Lin, and Chin Hsu*, 2019, “Targeting GPER1 to suppress autophagy as a male-specific therapeutic strategy for iron-induced striatal injury" Scientific Reports 9, Article number: 6661 (2019).
3. Chirra, S., Siliveri, S., Gangalla, R., Goskula, S., Gujjula, S. R., Adepu, A. K., Anumula, R., Sivasoorian, S. S., Wang, L. F., Narayanan, V.*, 2019, “Synthesis of new multivalent metal ion functionalized mesoporous silica and studies of their enhanced antimicrobial and cytotoxicity activities.” J Mater Chem B, 7 (45), 7235-7245. (IF=5.334, 9/38, Materials Science, Biomaterials)
4. Chien, C. M.; Yang, J. C.; Wu, P. H.; Wu, C. Y.; Chen, G. Y.; Wu, Y. C.; Chou, C. K.; Tseng, C. H.; Chen, Y. L.*; Wang, L. F.*; Chiu, C. C.*, Phytochemical naphtho[1,2-b] furan-4,5dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer. Phytomedicine 2019, 54, 109-119.
2018
1. Mi, Fwu-Long#, Wang, Li-Fang#, Chu, Pei-Yi, Peng, Shin-Lei, Feng, Chun-Lung, Lai, Ying-Jing, Li, Jia-Ni, Lin, Yu-Hsin*, 2018, “Active Tumor-Targeted co-Delivery of Epigallocatechin Gallate and Doxorubicin in Nanoparticles for Combination Gastric Cancer Therapy” ACS Biomaterials Science & Engineering, 4(8), 2847-2859 (IF 4.511, 8/32, MATERIALS SCIENCE, BIOMATERIALS)
2. Ming-Fong Tsai, Chin Hsu, Chen-Sheng Yeh, Yu-Jen Hsiao, Chia-Hao Su* and Li-Fang Wang*, 2018, “Tuning the Distance of Rattle-Shaped IONP@Shell-in-Shell Nanoparticles for Magnetically-Targeted Photothermal Therapy in the Second Near-Infrared Window”, ACS Applied Materials & Interfaces 2018, 10, 1508−1519 (IF: 8.758, 27/293, MATERIALS SCIENCE, MULTIDISCIPLINARY - SCIE)
3. Zi-Xian Liao*, Ivan M. Kempson*, Man-Jing Chen, Yu-Chen Fa, Kuo-Yen Huang, Li-Fang Wang*, 2018, “Micro-scale RNA Interference using Iron Oxide Nanoparticle-modified Lentivirus”, ChemNanoMat, 4, 98 –102 (IF: 3.379, Rank 86/293 MATERIALS SCIENCE, MULTIDISCIPLINARY - SCIE).
2017
1. Chun-Yi Chang, Shin-Pon Ju*, Li-Fang Wang*, Chien-Chia Chen, Ying-Chen Chuang, Hong-Lin Wu, and Hsin-Tsung Chen, 2017, “Investigation of the self-assembly of CS and PCL copolymers with different molecular weights in water solution by coarse-grained molecular dynamics simulation”, J Mol Model, 23: 151. (1.507)
2. Hsuan-Ying Chen, Yu-Lun Lo, Pei-Ling Wu, Pei-Chi Lo, Li-Fang Wang*, 2017, “Length effect of methoxy poly(ethylene oxide)-b-[poly(ε-caprolactone)-g-poly(methacrylic acid)] copolymers on cisplatin delivery”, Colloids and Surfaces B: Biointerfaces, 156(8), 243-253. (IF= 3.997, 13/72, Biophysics).
3. Someswara Rao Kosuru, Ting-Han Sun, Li-Fang Wang, Jaya Kishore Vandavasi, Wei-Yi Lu, Yi-Chun Lai, Sodio C. N. Hsu,* Michael Y\. Chiang,*, and Hsuan-Ying Chen*, 2017, Inorg. Chem. 56, 7998−8006.
4. Chieh-Ling Lee, Ya-Fan Lin, Man-Ting Jiang, Wei-Yi Lu, Jaya Kishore Vandavasi, Li-Fang Wang, Yi-Chun Lai, Michael Y. Chiang, and Hsuan-Ying Chen*, 2017, Organometallics, 36, 1936−1945.
5. Chiao-Yin Hsu, Hsi-Ching Tseng, Jaya Kishore Vandavasi, Wei-Yi Lu, Li-Fang Wang, Michael Y. Chiang, Yi-Chun Lai, Hsing-Yin Chen* and Hsuan-Ying Chen*, 2017, RSC Adv., 7, 18851–18860 (IF= 3.108, 59/166, Chemistry: Multidisciplinary).
6. Zi-Xian Liao,* Ivan M. Kempson,* Yu-Chen Fa, Meng-Chia Liu, Li-Chen Hsieh, Kuo-Yen Huang, and Li-Fang Wang*, 2017, “Magnetically guided viral transduction of gene-based sensitization for localized photodynamic therapy to overcome multidrug resistance in breast cancer cells”, Bioconjugate Chem. 28(5), 1702−1708 (IF= 4.485, 10/79, BIOCHEMICAL RESEARCH METHODS).
2016
1. Yu-Sheng Liu, Shih-Jer Huang, Xiao-Shan Huang, Yi-Ting Wu, Hsuan-Ying Chen, Yu-Lun Lo and Li-Fang Wang*, 2016, “The synthesis and comparison of poly(methacrylic acid)–poly(3-caprolactone) block copolymers with and without symmetrical disulfide linkages in the center for enhanced cellular uptake”, RSC Advances, 6(8), 75092–75103 (IF= 3.108, 59/166, Chemistry: Multidisciplinary).
2. Yu-Sheng Liu, Ru-You Cheng, Yu-Lun Lo, Chin Hsu, Su-Hwei Chen, Chien-Chih Chiu* and Li-Fang Wang*, 2016, “Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles” Nanoscale, 2016, 8, 3510–3522. (IF 7.367, 23/275, Material Science, Multidisciplinary)
3. Li-Fang Wang, Kazunari K. Yokoyama, Chih-Lung Lin, Tzu-Yin Chen, Hsiu-Wen Hsiao, Pei-Chi Chiang, Chin Hsu*, 2016, “Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice”, Scientific Reports, 6, 26358. (IF= 4.259, 10/64, Multidisciplinary Sciences)
4. Yu-Lun Lo, Hung-Wei Wang, Zi-Xian Liao, and Li-Fang Wang*, 2016, “The synthesis and comparison of chondroitin sulfate-modified PDMAEMA with chondroitin sulfate-modified PEI as a potential gene delivery vector”, RSC Advances, 6(5), 38209–38222 (IF= 3.108, 59/166, Chemistry: Multidisciplinary)
2015
1. Wang L-F, Yokoyama KK, Chen T-Y, Hsiao H-W, Chiang P-C, Hsieh Y-C, et al. 2015, ”Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy” PLoS ONE, 10(7): e0131224. (IF= 3.234, 8/56, Multidisciplinary Sciences)
2. Yu-Lun Lo, Han-Lin Chou, Zi-Xian, Liao, Shih-Jer Huang, Jyun-Han Ke, Chien-Chih, Chiu and Li-Fang Wang*, 2015, "Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for gene delivery" Nanoscale, 7, 8554 - 8565 (IF 7.660, 18/163, Chemistry, Multidisciplinary)
3. Guo-Jing Chen, Jyun-Han Ke, Chin Hsu, and Li-Fang Wang*, 2015, “Comparison of chemically and physically coated iron oxide nanoparticles with poly(ethylene glycol)-b- poly(ε-caprolactone)- g-poly(acrylic acid) for imaging and chemotherapy” Journal of Biomedical Nanotechnology, 11(6), 951-963 (IF= 3.929, 8/33 Mater Sci: Biomater).
4. Yu-Lun Lo, Pei-Chi Lo, Chien-Chih Chiu, and Li-Fang Wang*, 2015, “Folic acid linked chondroitin sulfate-polyethyleneimine copolymer based gene delivery system” Journal of Biomedical Nanotechnology 11 (8), 1385-1400. (IF= 3.929, 8/33 Mater Sci: Biomater).
2014
1. Yu-Sheng Liu1, Hsuan-Ying Chen1, Jay-An Yeh1, and Li-Fang Wang*, 2014, “Folate-mediated and doxorubicin-conjugated poly(ε-caprolactone)-g-chondroitin sulfate copolymers for enhanced intracellular drug delivery”, RSC Adv. 4, 59548-59557. (IF= 3.708, 35/148, Chemistry: Multidisciplinary).
2. Yu-Lun Lo, Pei-Chi Lo, Chien-Chih Chiu, and Li-Fang Wang*, 2014, “Folic acid linked chondroitin sulfate-polyethyleneimine copolymer based gene delivery system” Journal of Biomedical Nanotechnology (Accepted: Sep 9, 2014, doi:10.1166/jbn.2015.2081). (IF= 7.578, 2/32 Mater Sci: Biomater).
3. Yu-Chih Su, Yu-Lun Lo, Chi-Ching Hwang, Li-Fang Wang, Min Hui Wu, Eng-Chi Wang, Yun-Ming Wang and Tzu-Pin Wang*, 2014 “Azide–alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates” Biomol. Chem., 12, 6624-6633.
4. Guo-Jing Chen, Ying-Zhen Su, Chin Hsu, Yu-Lun Lo, Shih-Jer Huang, Jyun-Han Ke, Yung-Chih Kuo, Li-Fang Wang*, 2014, “Angiopep-pluronic F127-conjugated superparamagnetic iron oxide nanoparticles as a nanotheranostic agent for BBB targeting”, J. Material Chem. B., 2(34), 5666-5675. (IF=6.626, 22/251, Material Sci: Multidisciplinary).
5. Shih-Jer Huang, Zhi-Rong Hsu, and Li-Fang Wang*, 2014, “Synthesis and Characterization of Pluronic-block-Poly(N,N-dimethylamino-2-ethyl methacrylate) Pentablock Copolymers for Drug/Gene Co-delivery Systems”, RSC Adv., 4, 31552-31563. (IF= 3.708, 35/148, Chemistry: Multidisciplinary).
6. Yu-Shiang Peng, Po-Liang Lai, Sydney Peng, His-Chin Wu, Siang Yu, Tsan-Yun Tseng, Li-Fang Wang*, I-Ming Chu*, 2014, “Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier”, J. Nanomed, 9, 3163–3174. (IF=4.195, 32/254, Pharmacology & Pharmacy).
7. Guo-Jing Chen, Jyun-Han Ke, Chin Hsu, and Li-Fang Wang*, 2014, “Comparison of chemically and physically coated iron oxide nanoparticles with poly(ethylene glycol)-b– poly(ε-caprolactone)- g-poly(acrylic acid) for imaging and chemotherapy” Journal of Biomedical Nanotechnology, (doi:10.1166/jbn.2014.2012) (IF= 7.578, 2/32 Mater Sci: Biomater).
8. Yu-Sheng Liu, Chien-Chih Chiu, Hsuan-Ying Chen, Su-Hwei Chen* and Li-Fang Wang*, 2014 “Preparation of Chondroitin Sulfate-g-Poly(ε-Caprolactone) Copolymers as a CD44-Targeted Vehicle for Enhanced Intracellular Uptake” Molecular Pharmaceutics,11(4), 1164–1175 (IF= 4.782, 27/261).
9. Chih Su, Hsing-Yin Chen, Ni Chien Ko, Chi-Ching Hwang, Min Hui Wu, Li-Fang Wang, Yun-Ming Wang, Sheng-Nan Chang, Eng-Chi Wang, Tzu-Pin Wang*, 2014 “Effective and site-specific phosphoramidation reaction for universally labeling nucleic acids” Analytical Biochemistry, 449, 118–128 (IF= 2.582, 26/75).
10. Yu-Lun Lo, Guo-Jing Chen, Tzu-Hwa Feng, Ming-Han Li and Li-Fang Wang*, 2014 “Synthesis and characterization of S-PCL-PDMAEMA for co-delivery of pDNA and DOX” RSC Adv., 4, 11089–11098 (IF= 3.708, 35/148, Chemistry: Multidisciplinary).
2013
11. Shih-Jer Huang, Jyun-Han Ke, Guo-Jing Chen, and Li-Fang Wang*, 2013 “One-pot synthesis of poly(2-dimethyl amino)ethyl methacrylate-bound iron oxide nanoparticles for magnetofection” Mater. Chem. B, 1, 5916-5924 (IF=6.626, 22/251, Material Sci: Multidisciplinary).
12. Yu-Lun Lo, Kuo-Hsun Sung, Chien-Chih Chiu, Li-Fang Wang*, 2013 “Chemically Conjugating Polyethylenimine with Chondroitin sulfate to Promote CD44-Mediated Endocytosis for Gene Delivery" Molecular Pharmaceutics, 10(2), 664-676 (IF= 4.787, 24/254, Pharmacology & Pharmacy)
13. Yu-Lun Lo,Yao-Sheng Wang, and Li-Fang Wang*, 2013 “The Copolymer of Poly(2-dimethylaminoethyl methacrylate) and Methacrylated Chondroitin Sulfate with Low Cytotoxicity for Gene Delivery” Advanced Healthcare Materials, 2(11), 1458-1468. (IF=4.880, 5/32, Material Sci: Biomaterials)
14. Shih-Jer Huang, Tzu-Pin Wang, Sheng-I Lue, and Li-Fang Wang*, 2013 “ Pentablock Copolymers of Pluronic F127 and Modified Poly(2-dimethyl amino)ethyl Methacrylate for Internalization Mechanism and Gene Transfection Studies” Int J Nanomedicine, 8, 2011-2027. (IF=4.195, 32/254, Pharmacology & Pharmacy)
15. Shih-Jer Huang, Shou-Li Sun, Chien-Chih Chiu, and Li-Fang Wang*, 2013 “ Retinol- encapsulated water-soluble succinated chitosan nanoparticles for antioxidant applications” J Biomater Sci. Polym. Edn. 24, 315-329 (IF= 1.357, 48/82, Polymer Sci).
2012
16. Yue-Jin Lin, Yu-Sheng Liu, Hsin-Hwa Yeh, Tian-Lu Cheng, Li-Fang Wang*, 2012 “Self-assembled poly(epsilon-caprolactone)-g-chondroitin sulfate copolymers as an intracellular doxorubicin delivery carrier against lung cancer cells” Int J Nanomedicine, 7, 4169-4183 (IF= 4.976, 18/249).
17. Shuo-Li Sun, Yu-Lun Lo, Hsing-Yin Chen, and Li-Fang Wang*, 2012 “Hybrid Polyethylenimine and Polyacrylic Acid-bound Iron Oxide as a Magnetoplex for Gene Delivery” Langmuir 28(7), 3542- 3552 ( IF=4.269, 26/225)
18. Shao-Yun Wei, Li-Fang Wang, Yuan-Han Yang, Hsin-Hu Yeh, Yi-Chin Chen, Su-Hwei Chen*, 2012,” Sample stacking by field-amplified sample injection and sweeping for simultaneous analysis of acidic and basic components in clinic application” Electrophoresis, 33, 1571-1581 (IF= 3.569, 12/73).
19. Li-Fang Wang*, Hsiao-Chen Ni, Yue-Jin Lin, and Yu-Shen Liu, 2012 “Chondroitin Sulfate-g-Poly(ε-caprolactone) Copolymer Aggregates as a Targeting Drug Carrier” J Biomater Sci. Polym. Edn. 23(14), 1821-1842 (IF= 1.842, 25/79)
20. Li-Fang Wang*, Jenn-Shing Chen, and Yu-Lun Lo, 2012 “Novel Nanoparticles to encapsulate microRNA for the treatment of stroke” Ther. 20 (Suppl 1), S160-161. (IF= 6.873, 9/158, based on Biotechnology and microbiology)
21. Hsiu-Wen Hsiao, Ke-Li Tsai, Li-Fang Wang, Yen-Hsu Chen, Pei-Chi Chiang, Shu-Mien Chuang, Chin Hsu*, 2012, “The Decline of Autophagy Contributes to Proximal Tubular Dysfunction During Sepsis” Shock, 37(3), 289-296 (IF= 3.203, 20/188)
2011
22. Guo-Jing Chen and Li-Fang Wang*, 2011 “Design of Magnetic Nanoparticles-Assisted Drug Delivery System” Curr Pharm Design, 17(22), 2331-2351 (SCI, IF=4.774, 22/249)
23. Hun-Yu Tsai, Chien-Chih Chiu, Ping-Chih Lin, Su-Hwei Chen, Shih-Jer Huang, and Li-Fang Wang*, 2011, “The Antitumor Efficacy of Released Doxorubicin From Crosslinked Nanoparticulate Chondroitin Sulfate/Chitosan Polyelectrolyte Complexes” Macromol. Biosci., 11(5), 680-688 (SCI, IF=3.458, 12/79).
24. Elsie Khai-Woon Toh, Hsing-Yin Chen, Yu-Lung Lo, Shih-Jer Huang, Li-Fang Wang*, 2011 “Succinated Chitosan as a Gene Carrier for Improved Chitosan Solubility and Gene Transfection” Nanomedicine: NBM 7, 174-183. (SCI, IF= 6.930, 14/106)
25. Chien-Chih Chiu, Yin-Tzu Lin, Shuo-Li Sun, Kuo-Hsun Sung Li-Fang Wang*, and Jenn-Shing Chen, 2011, “Folate-mediated chondroitin sulfate/chitosan nanoparticulate polyelectrolyte complex as a drug carrier for doxorubicin delivery” J Biomaterial Sci: Polym. Edn. 22, 1487-1507 (SCI, IF= 1.842, 25/79).
2010
26. Jyun-Han Ke, Jia-Jyun Lin, James, R Carey, Jenn-Shing Chen, Chiao-Yun Chen, and Li-Fang Wang*, 2010,”A Specific Tumor-Targeting Magnetofluorescent Nanoprobe for Dual-Modality Molecular Imaging”, Biomaterials, 31, 1707-1715. (SCI, IF= 7.882, 2/69)
2009
27. Jia-Jyun Lin, Jenn-Shing Chen, Shih-Jer Huang, Jyun-Han Ko, Yu-Ming Wang, Ting- Lung Chen, and Li-Fang Wang*, 2009, ” Folic acid-Pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications” Biomaterials, 30, 5114-5124. (SCI, IF= 7.882, 2/69)
28. L. Lo, Y.S. Peng, B.H. Chen, L.F. Wang*, and K.W. Leong, 2009 “Poly(ethylene imine)-g-Chitosan Using EX-810 as a Spacer for Non-viral Gene Delivery Vectors” J Biomed Mater Res: Part A , 88A, 1058-1068. (SCI, IF= 3.044, 12/70)
29. Shih-Jer Huang, Shuo-Li Sun, Tzu-Hua Feng, Kuo-Hsun Sung, Wen-Ling Lui, and Li-Fang Wang*, 2009 “Folate-Mediated Chondroitin Sulfate-Pluronic® 127 Nanogels as a Drug Carrier” Eur. J. Pharm. Sci., 38, 64-73. (SCI, IF= 3.291, 68/249)