The Department of Medicinal and Applied Chemistry at Kaohsiung Medical University (KMUC) had the honor of hosting Prof. Aiichiro Nagaki from the Faculty of Science, Hokkaido University, a world-renowned expert in flow chemistry, for a special lecture on April 2, 2026.

Prof. Nagaki is an internationally recognized scholar in the fields of flow chemistry and microreactor-based synthesis. His research integrates organic synthesis with chemical engineering, focusing on the development of innovative continuous-flow reaction technologies. In particular, his work emphasizes the precise control of highly reactive and short-lived intermediates using microfluidic systems, leading to the concept of “flash chemistry,” which enables transformations that are difficult or even impossible to achieve under conventional batch conditions.

In this lecture, entitled “EMI in Flash Synthetic Chemistry Guided by Flow Microreactor Research,” Prof. Nagaki introduced how microreactors, with reaction times on the millisecond-to-second scale and precise control over temperature and mixing, can effectively suppress side reactions while enhancing selectivity and efficiency. This approach allows for the safe and controlled generation and rapid transformation of highly unstable or potentially hazardous intermediates.

In addition, Prof. Nagaki presented his recent advances in multistep flow synthesis, automated synthesis systems, and continuous processing technologies. These developments demonstrate the broad potential of flow chemistry in pharmaceutical synthesis, functional materials development, and fine chemical production. His work contributes to the transition from traditional batch processes to more efficient, scalable, and sustainable chemical manufacturing.

The lecture attracted enthusiastic participation from faculty members and students, with active discussions and engaging questions throughout the session, highlighting the vibrant academic atmosphere and international exchange within the department.